产品货号:
Z38432
中文名称:
GRB2抗体
英文名称:
Anti-GRB2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GRB2 Antibody |
指标别名 | Adapter protein GRB2;ASH;EGFRBP GRB2;GRB2;Grb3 3;MST084;MSTP084;Protein Ash;SH2/SH3 adapter GRB2 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | GRB2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human GRB2 Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. |
实际分子量 | 25KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | GRB2,Growth factor receptor-bound protein 2,is an adaptor protein involved in signal transduction/cell communication.The GRB2 gene encodes a protein that has homology to noncatalytic regions of the SRC oncogene product.Its two SH3 domains direct complex formation with proline-rich regions of other proteins,and its SH2 domain binds tyrosine phosphorylated sequences.In humans,the GRB2 protein is encoded by the GRB2 gene.Grb2 is widely expressed and is essential for multiple cellular functions.The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains.Its two SH3 domains direct complex formation with proline-rich regions of other proteins,and its SH2 domain binds tyrosine phosphorylated sequences.This gene is similar to the sem-5 gene of Caenorhabditis elegans,which is involved in the signal transduction pathway.Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Uniprot ID | P62993 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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